Diabetes is definitely one of the major health concerns in today’s world. It is also one of the most disturbing ones since to date there is no known cure for this disease. The best that diabetics can do is manage their symptoms. One of the numerous factors that have been associated with diabetes is human growth hormone (HGH). Get more information at the Anti Aging Ninjas blog where they they ask the question; Does this substance help to improve or make diabetes worse?
HGH and Diabetes
Diabetes is a disease that is the result of your body being unable to effectively use sugar. The foods that you normally eat, carbohydrates specifically, get broken down into glucose in your body. These sugars are carried into the various parts of your body that need them.
In order for this process to run effectively, you need to have a sufficient amount of hormone insulin. That is what moves glucose into the cells from your blood. Type 1 diabetes occurs when not enough of this hormone is produced by the pancreas. With type 2 diabetes, there might be enough insulin, but the cells of the body are insensitive to the insulin. In either case, blood sugar levels surge, which brings about diabetes symptoms.
HGH (human growth hormone) is a critical substance that occurs in the body naturally. It plays a major role in numerous processes. It is critical for the development and growth of children, but also promotes good health for individuals of all ages.
However, like other hormones in the body, as people age HGH levels drop. That can bring about certain negative changes, which includes various medical conditions and signs of aging. Some people also claim that this decline contributes to the development of diabetes also. This suggests that HGH supplementation might help to manage diabetes.
How HGH Might Help With Diabetes
HGH is not a regular treatment option you hear discussed for diabetes. However, there are certain actions that are attributed to HGH that might help to manage the disorder.
Helps To Improve Glucose Metabolism
It is thought that growth hormone might help with regulating how much sugar is in the bloodstream. IGF-1, which is insulin-like growth factor 1, is another substance that helps to mediate HGH action. The hormone mimics insulin action. That helps to improve glucose absorption from the blood. What IGF-1 does is help to make sure it gets into the tissues and cells where these sugars are needed for growth, energy, and respiration.
Reduces Cholesterol Levels and Body Fat
Obesity and being overweight greatly contribute to diabetes. They cause the release of harmful chemicals that can disrupt the effectiveness of glucose metabolism. This results in glucose not being able to work its way out of the blood.
When the blood contains high cholesterol levels is increases the risk of diabetes. That is due to the fact that cholesterol deprives the cells of the body of glucose. Sugar is absorbed which increases the levels in your blood. Growth hormone can help keep cholesterol levels under control.
Insulin Sensitivity Is Enhanced
Due to the above, some claim that HIGH might help the pancreas produce more insulin. IGF-1 also removes glucose from your bloodstream which results in the liver and pancreas not having to work so hard.
Improved glucose metabolism can also help to improve insulin sensitivity. With lower amounts of sugar to deal with, it is easier to move the sugar out of the blood. Reduced cholesterol and fat help to improve insulin sensitivity as well.
Some research suggests that HGH might help with managing diabetes. In some cases, however, this is not directly indicated. For instance, some find that growth hormone reduces body fat or improves glucose metabolism.
Research conducted at Johns Hopkins Institute found that HGH helps to improve insulin sensitivity and manage visceral fat. It was suggested by the researchers that proper usage of HGH might be useful in helping to control diabetes symptoms.
Researchers in Belgium found that HGH might help to facilitate the production of insulin (1) After an HGH gene was injected into mice, they found that they start producing growth hormone, like what happens when the animals are pregnant. In turn, this led to an increased number of cells producing insulin in the pancreas. This resulted in the increase of diabetes-controlling hormone.
Another team of researchers in Belgium found that a deficiency of growth hormone increase risk for type 2 diabetes. They found a higher occurrence of diabetes in HGH deficient individuals compared to those who were not HGH deficient.(2)
The relationship between HGH and diabetes is not always a positive one. In some cases, using HGH resulted in diabetes and can cause insulin resistance. It is said that HGH can cause the release of high levels of free fatty acids into the blood which impedes glucose from being efficiency transported into the body’s cells. There is an inverse relationship between insulin levels and growth hormone. When one increases, the other one decreases.
The body increases insulin production to deal with this issue. This continues until the cells become insulin insensitive, which is synonymous with type 2 diabetes.
Arguments for both the negative and positive effects of HGH on diabetes might seem confusing. The difference appears to be in how long and frequently you take HGH. It is thought to be safe for managing diabetes when taken in low doses and not taken for long uninterrupted periods of time.
Ref (1) & (2): https://www.ncbi.nlm.nih.gov/